Cyclooxygenase inhibition: between the devil and the deep blue sea

Cyclooxygenase inhibition: between the devil and the deep blue sea.

Non-steroidal anti-inflammatory drugs (NSAIDs) account for more reports of drug related toxicity than any other class of drugs. Their most widely recognised adverse effects are on the gastrointestinal tract. They cause acute erosions and chronic ulcers that result in hospitalisation and death because of ulcer bleeding and perforation. Between them, aspirin and non-aspirin NSAIDs may account for...

Between the devil and deep blue sea.

This inspiring book becomes one that is very booming. After published, this book can steal the market and book lovers to always run out of this book. And now, we will not let you run out any more to get this book. Why should be between the devil and deep blue sea? As a book lover, you must know that enjoying the book to read should be relevant to how you exactly need now. If they are not too mu...

The devil and the deep blue sea.

Management of dementia-related agitation: between the devil and the deep blue sea.

WHAT IS ALREADY KNOWN ON THIS TOPIC? Dementia-related agitation is a common and costly condition that is distressing, debilitating, often dangerous and usually difficult to treat in a safe and reliable manner. Clinicians are caught between the ‘devil’ of medications with unfavourable risk–benefit profiles and the ‘deep blue sea’ of non-pharmacological interventions perceived as impractical and ...

Stopping aspirin before coronary artery surgery: between the devil and the deep blue sea.

Coronary artery bypass grafting (CABG) aims to reduce immediate and longer-term risks of myocardial infarction and death in patients with coronary artery disease. CABG is, however, associated with its own thrombotic risks of perioperative myocardial infarction, stroke, pulmonary embolism, and bowel infarction.1 These risks are of major concern to the patient and referring cardiologist. Although...